On 13.9.2011 Microsoft released Important Security bulletin regarding Vulnerabilities in Microsoft SharePoint http://support.microsoft.com/kb/2451858. The update was automatically deployed and installed via WSUS or Microsoft Update. If your SharePoint server did not had SP1 installed you are affected with problem that you cannot access My Site settings in Central Administration.

Solutions to this issue is installation of Service Pack 1 for SharePoint Server and August Cumulative Update

http://www.microsoft.com/download/en/details.aspx?id=26623

http://blogs.technet.com/b/stefan_gossner/archive/2010/09/02/august-2010-cumulative-update-for-sharepoint-has-been-released.aspx

More on this can be read here: http://blogs.technet.com/b/stefan_gossner/archive/2011/09/19/update-on-september-security-bulletin-ms11-074-and-sharepoint-2010-issues.aspx

 

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